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AICAR (AICA) Ribonucleotide 100mg

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0.10 LBS
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Product Description

Buy AICAR (AICA) Ribonucleotide 100mg

AICA ribonucleotide or AICAR (aminoimidazole carboxamide ribonucleotide) is an intermediate in the generation of inosine monophosphate, which acts as an AMP-activated protein kinase agonist.[1] It stimulates glucose uptake and increases the activity of p38 mitogen-activated protein kinases α and β in skeletal muscle tissue,[2] as well as suppressing apoptosis by reducing production of reactive oxygen compounds inside the cell.[3] In 2008, researchers at the Salk Institute discovered that AICAR given to experimental mice significantly improves their performance in endurance-type exercise, apparently by converting fast-twitch muscle fibers to the more energy-efficient, fat-burning, slow-twitch type. They also looked at the administration of GW 501516 (also called GW1516) in combination with AICAR. Given to mice that did not exercise, this combination activated 40% of the genes that were turned on when mice were given GW1516 and made to exercise. This suggests it may be possible to obtain some of the benefits of exercising without actually exercising.[4] Because of the enhanced endurance effects, this could potentially be used by athletes to enhance their performance. One of the lead researchers from this study has developed a urine test to detect it and has made the test available to the International Olympic Committee, and the World Anti-Doping Agency has added AICAR to the prohibited list from 2009 onwards.

Buy AICAR (AICA) Ribonucleotide

AICAR (AICA) Ribonucleotide Peptides:
Harmful if swallowed. Irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water. During research wear suitable protective clothing and gloves. Keep unprotected persons away. For use only by qualified researchers. Water hazardous. Research in a well ventilated area. Do not breathe dust, vapor, mist or gas. Do not ingest or inhale. Use safety glasses face protection. Disposal must be made according to official regulations. Wash hands after handling. Store in a cool dry place. Usual precautionary measures should be adhered to in handling the chemicals & peptides. The product is for research use only. This product is not for human use. 

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